Active Pharmaceutical Ingredients
Our special added value in micronization of Active Pharmaceutical ingredients is:
-
Specifications of d(0.9)<5 microns are consistently obtained
-
Only one pass in the mill is required, where other micronizers need two or more passes (sometimes with cryogenic feed).
-
Lower air consumption compared to other micronizers implies lower installation and operating costs.
We successfully micronize Active Pharmaceutical Ingredient For challenging applications on full commercial scale:
-
Corticosteroid: Inhalation grade with narrow spec for mean particles of about 2 microns
-
Long acting beta-adrenoceptor agonist(LABA) and Long-acting muscarinic antagonist (LAMA): Inhalation grade of poor-flowing material with d(0.9) under 3 microns.
-
Blood-pressure lowering agent- extremely sticky and non-flowing API
-
Cholesterol lowering drug – d(0.9) of 5 microns is consistently achieved in one pass
The system conforms to gmp, can be designed to handle potent materials and can be operated in aseptic conditions.
Corticosteroid for inhalation
d(10)=0.68 d(50)=1.234 d(90)=1.936
Bronchodilator for inhalation
d(10)=0.404 d(50)=0.986 d(90)=2.697
Cardio Vascular agent –
d(10)=0.44 d(50)=0.774 d(90)=1.632
New generation anti diabetic agent –
d(10)=0.798 d(50)=1.658 d(90)=3.085
Severe metabolic disorder treatment agent –
d(10)=1.126 d(50)=2.503 d(90)=4.902
Amino Acid –
d(10)=1.051 d(50)=3.627 d(90)=8.946
